Ymc Carotenoid Column | Case Studies – Customer Data From Capturesmb Experiences Of Twin-Column System 98 개의 정답

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Experience of multiple end-users employing GMP scale pilot systems using twin-column continuous capture and sequential batch (polishing) chromatography on actual mAb feed-stock will be presented. Economics as modeled by end-users are shown in this video 30 minute (+ Q\u0026A) webinar.
Continuous downstream processing is increasingly evaluated and implemented in the biopharmaceutical industry. In the capture of monoclonal antibodies using protein A affinity chromatography, periodic counter-current processes have been described. While general process principles have been fully understood, the focus has shifted to manufacturing-related aspects such as scale-up, control and validation.
During this webinar a number of case studies showing the successful operation of a twin-column capture process (CaptureSMB) for monoclonal antibodies in GMP pilot scale are reviewed. Compared to traditional batch chromatography, specific productivity and resin capacity utilization by up to 2-3 fold and 30-40%, respectively.

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HPLC Columns, YMC Carotenoid – VWR

HPLC Columns, YMC Caroteno … The Caroteno C30 stationary phase proves sufficient phase thickness to enhance interaction with long chain molecules …

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Source: us.vwr.com

Date Published: 1/24/2022

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주제와 관련된 더 많은 사진을 참조하십시오 Case studies – customer data from CaptureSMB experiences of twin-column system. 댓글에서 더 많은 관련 이미지를 보거나 필요한 경우 더 많은 관련 기사를 볼 수 있습니다.

Case studies – customer data from CaptureSMB experiences of twin-column system
Case studies – customer data from CaptureSMB experiences of twin-column system

주제에 대한 기사 평가 ymc carotenoid column

  • Author: YMC America / Process Technologies
  • Views: 조회수 120회
  • Likes: 509891 Like
  • Date Published: 2020. 6. 2.
  • Video Url link: https://www.youtube.com/watch?v=HN2THf7fNRg

YMC Carotenoid C30

Columns, Guards and Accessories are only available for purchase online in North America or through our distributors.

To purchase consumables outside North America, please find your local distributor.

For YMC systems’ sales outside of North America and Europe, find your regional office contact information here.

YMC Carotenoid HPLC Column, C30, 5 µm, 250 mm x 4.6 mm

– C30 chains

– very lipophilic

– exceptional selectivity pattern

– isomer recognition

– polar carotenes

– polar and nonpolar xanthophylls

– steroids

– retinols

– fat-soluble vitamins

– LC-MS applications

General

The separation of geometric and positional isomers is a challenging task in reversed phase chromatography. Subtle molecular differences have to be recognized and resolved by this particular stationary phase. Sander et al. have conclusively shown that polymeric C30 HPLC stationary phases are able to discriminate isomeric structures of long chain molecules.

Properties

Compared to classical C18 stationary phases, YMC Carotenoid is much more hydrophobic. Even when pure organic eluents are applied, many sample solutes are retained. The use of non-aqueous reversed phase mobile phases facilitates 100% solvent recycling and LC-MS applications. The YMC Carotenoid stationary phase provides sufficient phase thickness to enhance interaction with long chained molecules (see figure on right). Therefore, geometric and positional isomers of conjugated double bonding systems are recognised and resolved by the YMC Carotenoid phase. The resolving power of YMC Carotenoid for isomers can be verified by the separation of carotenoids, which has been subject of considerable research efforts in the past. Carotenoids are found in a variety of natural sources including fruits and vegetables. In addition, carotenoids are considered as potential drugs for cancer intervention or prevention. Despite the complexity of carotenoid extracts and the minor shape differences between carotenoid isomers, the separation, identification and quantification of these compounds can be achieved by using YMC Carotenoid columns.

Applications

YMC Carotenoid columns are successfully used in the food industry, for the analysis of vitamin formulations, in environmental analysis, and for the control of algal growth. Other potential applications include the separation of prostaglandins and leucotrienes.

HPLC Columns, YMC Carotenoid

CT99S05-0504WT CT99S03-1546WT CT99S03-1003WT CT99S05-0546WT CT99S05-02Q1GC CT99S03-1503WT CT99S03-0504WT CT99S05-2546QT CT99S05-01Q1GC CT99S05-1546WT CT99S05-0502WT CT99S05-2510WT CT99S03-0503WT CT99S05-1046WT CT99S05-0204GC CT99S05-2502WT CT99S03-2502WT CT99S05-1002WT CT99S05-0520WT CT99S03-1046WT CT99S05-2546WT CT99S05-2520WT CT99S05-0503WT CT99S03-0546WT CT99S03-2546WT CT99S03-1002WT CT99S05-1502WT CT99S05-1503WT CT99S03-0204GC CT99S03-0502WT CT99S03-1502WT CT99S05-1520WT CT99S05-2503WT

HPLC Columns, YMC Carotenoid

Chromatography Columns

The Carotenoid C30 stationary phase provides sufficient phase thickness to enhance interaction with long chain molecules therefore, geometric and positional isomers of conjugated double-bonding systems are recognized and resolved.

These columns is much more hydrophobic and lipophilic

Even when pure organic eluents are applied, many sample solutes are retained

Applicable for LC-MS

Carotenoids are found in a variety of natural sources including fruits and vegetables. In addition, carotenoids are considered as potential drugs for cancer intervention and/or prevention. Despite the complexity of carotenoid extracts and the minor shape differences between carotenoid isomers, the separation, identification, and quantitation of these compounds can be achieved using these columns.

YMC Carotenoid Column, 3um, 250 x 4.6mm

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